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CDK4 — PRDX2
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Sowa et al., Cancer Res 1999
:
We previously reported that both sodium butyrate and
trichostatin A (TSA) , both of which are known as inhibitors of histone deacetylase, arrest human tumor cells at G1 and G2-M and
activate the
cyclin dependent kinase inhibitor, the p21/WAF1/Cip1 gene promoter, through the Sp1 sites
Park et al., Int J Mol Med 2008
(Breast Neoplasms...) :
In addition,
TsA markedly
down-regulated the expression of cyclin D1 and
CDK4 , up-regulated the expression of p21WAF1 and p53 and induced cell cycle arrest at the G1 phase in MCF10A-ras cells