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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Toma et al., Biochem Biophys Res Commun 2009 (Hyperglycemia...) : AGE-LDL stimulated p22(phox) expression by activating p38 MAP kinase and NF-kB, and MCP-1 expression by activating NF-kB, as demonstrated by the use of specific inhibitors ( SB203580 and Bay11-7085 ) ... The addition of 25mM glucose in the culture medium enhanced the effect of AGE-LDL , but also of nLDL, on RAGE, p22(phox) , NOX4, p67(phox), and MCP-1 gene expression
Zhao et al., Free radical research 2011 : The present study demonstrated that oxidized LDL ( oLDL ) increased the generation of superoxide and hydrogen peroxide ( H ( 2 ) O ( 2 ) ), the abundances of NADPH oxidase (NOX)4, NOX2, p22-phox and lectin-like oLDL receptor-1 ( LOX-1 ) in wild-type or heat shock factor-1 (HSF1)-deficient mouse embryo fibroblasts (MEF)
Fu et al., Vascul Pharmacol 2013 : Our results showed that in the presence of ox-LDL , XJP-1 significantly attenuated ox-LDL mediated cytotoxicity, apoptosis, caspase-3 activation, reactive oxygen species ( ROS ) generation, and NADPH oxidase subunit ( p22phox and p47phox ) expression in HUVECs