Wu et al., Environ Toxicol 2013
:
Western blot analysis demonstrated that propofol promoted Fas , cytochrome c, caspase-9 and -3 active form and Bax levels, but inhibited Bcl-xl protein level which led to cell apoptosis
Srinivasan et al., J Biol Chem 1998
(Breast Neoplasms) :
Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells ... In some cells, Bcl-xL overexpression can inhibit anti-Fas- and tumor necrosis factor (TNF)-alpha induced apoptosis