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Ding et al., J Leukoc Biol 2000
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Tumor necrosis factor alpha (TNF-alpha) and interleukin-1 (IL-1) increased endothelial adhesion molecule ( CAM ) expression, whereas interferon-gamma (IFN-gamma) induced little up-regulation of CAM Jiang et al., Neurochem Int 1997
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Since adhesion molecules ( AM ) induced on endothelial cells ( EC ) play an important role in T-cell migration into the CNS, the objective of this study was to examine the effect of IFN beta-1b on the expression of the AM, ICAM-1, V-CAM and E-selection induced on EC by IFN-gamma , TNF-alpha, or IL-1 beta