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IFNA6 — IFNG
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Shen et al., BMC cell biology 2002
:
Rat interferon-beta and
interferon-gamma significantly inhibited rat hepatic stellate cell proliferation while rat
interferon-alpha did not
affect the cell proliferation under the same culture condition
Radaeva et al., Biochem J 2004
(Carcinoma, Hepatocellular...) :
Interferon-gamma inhibits interferon-alpha signalling in hepatic cells : evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C
Benson et al., Graefes Arch Clin Exp Ophthalmol 1992
:
However, this expression was not maximal, and all the RPE lines tested showed a marked capacity for up-regulation of expression by culture in the
presence of
interferon-alpha ,
interferon-gamma , or tumour necrosis factor alpha, cytokines involved in immunological responses
Wysocka et al., Clin Lymphoma Myeloma 2007
(Lymphoma, T-Cell, Cutaneous...) :
Patients ' peripheral blood mononuclear cells ( PBMCs ) stimulated with the TLR7 agonist 3M-001 produced high levels of
interferon ( IFN ) -alpha , and the TLR8 agonist 3M-002 potently
induced predominantly interleukin (IL)-12 and
IFN-gamma
Bergmann et al., Nat Immun Cell Growth Regul 1990
(Melanoma) :
Therefore, we investigated the
effect of
interferon-alpha ( IFN-alpha ) , IFN-gamma and tumor necrosis factor ( TNF-alpha ) on the induction of LAK activity by IL-2, and the induction of
IFN-gamma and TNF-alpha by IL-2
Hertzog et al., Biochem Int 1989
:
Contrary to previous reports, C. parvum
induced predominantly
interferon gamma , which is normally acid labile, whereas poly I : poly C induced an acid labile
interferon alpha activity with characteristics similar to those of acid labile interferon alpha reported in serum in certain human diseases
Roberts et al., Proc Soc Exp Biol Med 1986
(Neoplasms) :
Exposure of the cells to moderate hyperthermia did not alter leukocyte production of
interferon-alpha in
response to influenza virus or
interferon-gamma in response to the mitogen phytohemagglutinin
Zhou et al., J Interferon Cytokine Res 1995
(Leukemia L1210) :
Exogenous
interferon-gamma induces endogenous synthesis of
interferon-alpha and -beta by murine macrophages for induction of nitric oxide synthase
Turpaev et al., Eur J Biochem 1996
:
The Trp-tRNA synthetase gene is
induced by
interferon-gamma in both lines and, in MT-4 lymphocytes, also by
interferon-alpha