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IRF5 — STAT1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: STAT1 → IRF5 (increases, STAT1 Activity)
  Evidence: TABLE V Selected genes up-regulated by IRF-5

Text-mined interactions from Literome

Guo et al., J Immunol 2005 : IRF-2 constitutively binds to the two ISRE/IRF-E sites at the DRR, while IRF-1 and STAT1 are induced to bind to the two ISRE/IRF-E sites and the ISRE/IRF-E1, respectively, only after IFN-beta treatment
Huang et al., J Clin Invest 2007 (Inflammation...) : Enforced expression of STAT1, IRF-1 , or GATA-1 enhanced phosphorylation of STAT1 , STAT3, and STAT5 in cultured Gata1-deficient murine megakaryocytes, with concomitant megakaryocyte maturation
Nguyen et al., Oncogene 1997 : Most strikingly, induction of IRF-1 and IRF/RelA expression resulted in a significant increase in STAT1 ( p91 ) protein and increased ISGF3 DNA binding activity, suggesting that IRF-1 tumor suppressor activity may involve a novel mechanism which activates the JAK-STAT pathway through STAT1