Gene interactions and pathways from curated databases and text-mining

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EPHB6 — RAC1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Penzes et al., Neuron 2003 : Activation of the EphB receptor induces translocation of the Rho-GEF kalirin to synapses and activation of Rac1 and its effector PAK
Holland et al., J Biol Chem 1997 : There is evidence that the Rho GTPases Rac and Cdc42 are also required for dorsal closure, suggesting that Rac or Cdc42 may regulate Hep and Bsk