◀ Back to TLR3

ICAM1 — TLR3

Text-mined interactions from Literome

Boyd et al., Cardiovasc Res 2006 (Myocarditis) : Ligand activation of TLR2, TLR4 and TLR5, but not TLR3, TLR7 or TLR9, resulted in cardiomyocyte expression of the inflammatory cytokine IL-6, the chemokines KC and MIP-2, and the cell surface adhesion molecule ICAM-1
Xie et al., Cell Microbiol 2008 (Otitis Media with Effusion) : ICAM-1 upregulation on human monocytes by the LOS required surface CD14, TLR4 , NF-kappaB p65 and c-Jun N-terminal kinase (JNK) activity
Farina et al., Ann Rheum Dis 2011 (Scleroderma, Systemic) : dsRNA/poly ( I:C ), but not other TLR ligands, highly stimulated ET-1 protein and mRNA ( EDN1 ), as well as intercellular adhesion molecule-1 ( ICAM-1 ) and IFN regulated MX2, by endothelial cells and dermal fibroblasts ... Together these data show that the dsRNA can regulate genes associated with vascular activation, as seen in SSc, that type I IFNs do not mediate these effects, and that EDN1 and ECE1 but not ICAM-1 activation is mediated by TLR3
López et al., Int J Cardiol 2012 (Aortic Valve Stenosis...) : Strikingly, when TLRs sensing viral patterns were studied, a sustained TLR3 mediated activation of NF-?B, a ?B-independent induction of catalytically active cyclooxigenase (COX)-2 and ICAM-1 expression, and induction of expression of several chemokines were observed