◀ Back to MAPK1

AVP — MAPK1

Text-mined interactions from Literome

Chen et al., Endocrinology 1999 : AVP and TPA, but not A23187, induced an increase in activity and tyrosine phosphorylation of p42 MAPK , together with a molecular weight shift, consistent with phosphorylation, of cytosolic PLA2 ... AVP and TPA, but not A23187, induced an increase in activity and tyrosine phosphorylation of p42 MAPK , together with a molecular weight shift, consistent with phosphorylation, of cytosolic PLA2
Qiao et al., Zhongguo Yao Li Xue Bao 1998 : The main findings are : ( 1 ) The AVP4-8 stimulated MAPK activity and the CaMKII autophosphorylation were blocked by ZDC ( C ) PR, an antagonist of AVP4-8, and also completely inhibited by pertussis toxin, a selective inhibitor of the G-protein coupled receptor ( GPCR ) ... But, AVP induced MAPK activation was not sensitive to ZDC ( C ) PR or PTX
Higashiyama et al., Hypertens Res 1999 : AVP activated mitogen activated protein ( MAP ) kinase , which was significantly reduced by 1 ng/ml TGF-beta1
Wang et al., Acta Pharmacol Sin 2000 : The main findings were : ( 1 ) AVP4-8 induced the MAPK activity in rat brain astroglial culture but not in fetal neuronal cultures ... AVP4-8 can activate the MAPK activity in astrocytes but not in fetal neuronal culture
Chiu et al., Am J Physiol Cell Physiol 2002 : AVP induces extracellular signal related kinase ( ERK)-1 (p44(mapk) ) and ERK-2 ( p42(mapk) ) activation, a response prevented by treatment with mitogen activated protein kinase kinase ( MEK ) inhibitors ( PD-98059 and U-0126 ), specific PKC inhibitors ( GF-I and Ro-31-8220 ), depletion of Ca ( 2+ ) ( EGTA and thapsigargin ), selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors ( tyrphostin AG-1478, compound 56 ), or the selective Src family kinase inhibitor PP-2
Nakatani et al., Biochem Biophys Res Commun 2007 : Treatment of 3Y1 cells with AVP resulted in transient activation of p44/42 mitogen activated protein kinase ( MAPK ) and cPLA(2)alpha, and phosphatidylinositol 3-kinase (PI3K) inhibitor blocked not only AVP induced PGE ( 2 ) synthesis but also MAPK activation, suggesting that PI3K is involved in the AVP induced MAPK and cPLA(2)alpha activation, which initiates the production of PGE ( 2 )
Yamada et al., Kidney Int 1995 : We conclude that AVP inhibits EGF stimulated Raf-1-K, MAPKK, MAPK , and S6K activity via cAMP in MDCK cells
Okada et al., Biochem Biophys Res Commun 1994 : The preincubation of vascular smooth muscle cells ( VSMC ) with a non-peptide arginine vasopressin (AVP) antagonist ( OPC-21268 ) ( 0.5 mM ) for 10 min completely inhibited the 1 microM AVP induced activation of mitogen activated protein ( MAP ) kinase but did not affect the angiotensin II-, protein kinase C activator- or ionomycin stimulated MAP kinase
Ishikawa et al., J Clin Invest 1994 : Furthermore, 1 x 10 ( -7 ) M AVP significantly activated mitogen activated protein kinase from 14.0 to 24.5 pmol/mg protein
Aharonovitz et al., J Biol Chem 1996 : In contrast, both AVP induced MAPK and NHE activities were inhibited by genistein and MEK inhibitor but were not affected by staurosporine
Ishikawa et al., Kidney Int 1996 (Hypertension) : Also, the AVP activation of mitogen activated protein ( MAP ) kinase and [ 3H ] thymidine incorporation was significantly exaggerated in cells of SHR compared with those of WKY
Kusaka et al., Endocrinology 1996 : AVP activated mitogen activated protein ( MAP ) kinase in a concentration dependent manner
Bataller et al., Gastroenterology 1997 : Moreover, AVP increased MAPk activity, DNA synthesis, and cell number
Tahara et al., J Cardiovasc Pharmacol 1997 (Hyperplasia...) : In addition, YM087 potently and concentration-dependently inhibited AVP induced increase in intracellular free calcium concentration and activation of mitogen activated protein kinase
Tahara et al., Cardiovasc Res 1998 : The effects of AVP and YM087 on intracellular free calcium concentration ( [ Ca2+ ] i ), mitogen activated protein ( MAP ) kinase and [ 3H ] -leucine incorporation were investigated in cultured neonatal rat cardiomyocytes