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Takano et al., Biochim Biophys Acta 2007
:
When the expression of CD4 was reduced by siRNA transfection, both CD4 dependent adhesion and MAPK activation were diminished
Cannon et al., Cancer Immunol Immunother 2013
(Ovarian Neoplasms) :
Modulation of p38 MAPK signaling enhances dendritic cell activation of human CD4 ( + ) Th17 responses to ovarian tumor antigen
Pallier et al., Int Immunol 1998
:
Differential CD4 dependent inhibition of JNK but not Erk-2 activities in human naive and memory CD4+ T cell populations ... The aim of the present report was to study the sensitivity of the naive and memory CD4+ T cell populations to the CD4 mediated inhibition of Erk-2 and JNK activation
Jauliac et al., Eur J Immunol 1998
:
Two major pathways implicated in T cell activation are inhibited by binding of CD4 ligands to the CD4 molecule, i.e. Ca2+ signaling by phospholipase Cgamma1 ( PLCgamma1 ), and ERK-2 activation , suggesting a p21ras inhibition