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PLD6 — WDR61

Text-mined interactions from Literome

Lenoir et al., Biochem Pharmacol 2002 : By contrast, GKB did prevent the Paf mediated PLD activity and CL response ( IC ( 50 ) of 2 microM )
Corl et al., Biochem Biophys Res Commun 2003 : The direct effects of PLD and PA on Lyso-PAF-AcT activity were assessed using selective inhibitors and repletion experiments
Balsinde et al., J Biol Chem 1991 : The activation of phospholipase D by platelet activating factor (PAF) in the human promonocytic cell line U937 has been investigated ... On the other hand, the data herein presented suggest that influx of external calcium is required for phospholipase D activation by PAF , as assessed by complete inhibition of the enzyme activity by chelation of extracellular calcium or by treatment with the calcium channel blocker verapamil
Wang et al., Chin J Physiol 2013 : Differential inhibitory effects of 2-azafluorenones on PI-PLC activation but not on PC-PLC- or PC-PLD-activation induced by histamine, PAF , PMA or A23187 in C6 glioma cells
Liu et al., Biochem Biophys Res Commun 1995 : Implication of protein kinase C alpha in PAF stimulated phospholipase D activation in Chinese hamster ovary ( CHO ) cells expressing PAF receptor ... Protein kinase C ( PKC ) isozyme ( s ) involved in regulation of platelet activating factor (PAF) induced phospholipase D ( PLD ) activation was investigated in CHO cells stably expressing cloned guinea-pig PAF receptor ( WT-H cells ) ... This kinetics was well correlated with PAF induced transient PLD activation ... These data suggest that PKC alpha is involved in the regulation of PAF stimulated PLD activation in WT-H cells
Liu et al., J Biochem 1994 : Platelet activating factor (PAF) activated phospholipase D ( PLD ) in WT-H cells, CHO cells stably expressing cloned guinea-pig PAF receptor ... PTK inhibitors ST-638 and genistein inhibited PLD activation induced by PAF as well as phorbol myristate acetate, indicating that PTK acts downstream of PKC
Mizunuma et al., Biochim Biophys Acta 1993 : The PLD was shown to be activated by phorbol, 12-myristate, 13-acetate ( PMA ), calcium ionophore A23187, oxytocin, bombesin and bradykinin, but not by platelet activating factor (PAF) and epidermal growth factor (EGF)
Ahmed et al., Cell Signal 1995 : TPA stimulated PLD activity in a dose dependent manner whereas PAF had no significant effect on PLD activity ... TPA ( 10 nM ) and PAF ( 100 nM ) stimulated PLD activity ... However, TPA stimulated PLD activity levels fell 10-fold while PAF mediated PLD activity remained elevated at 10 nM and 100 nM concentrations of 17 beta-oestradiol suggesting a different mechanism of activation ... These results indicate that 17 beta-oestradiol can upregulate PAF induced PLD activity in HEC-1B cells
Balsinde et al., Biochem J 1997 (Leukemia P388) : Furthermore, PMA activated phospholipase D ( PLD ) in these cells, and potentiated the effect of the inflammatory lipid mediator platelet activating factor (PAF) on PLD activation
Liu et al., Biochem J 1997 : In these cells, PAF induced PLD activation lasted for more than 20 min ... Propranolol and butanol at concentrations that inhibited the formation of DG suppressed the PAF induced mRNA expression of c-fos and c-jun. Taken together, the prolonged PLD activation in D-H cells confirmed a primary role for phospholipase C/PKC in PLD activation by PAF