◀ Back to BMP15

ALK — BMP15

Text-mined interactions from Literome

Sun et al., Biochem Biophys Res Commun 2007 (Hernia, Umbilical) : Abrogation of Alk3 mediated BMP signaling in this mouse resulted in severe defect of secondary ventral body wall formation, replicating the omphalocele phenotype in human
Hartwig et al., J Am Soc Nephrol 2008 : BMP receptor ALK3 controls collecting system development ... In summary, normal kidney development requires ALK3 dependent BMP signaling, which controls ureteric bud branching
Joziasse et al., Eur J Hum Genet 2011 (Down Syndrome...) : These data indicate that in the context of a DS background, ALK2 mediated reduction of BMP signaling may contribute to CHDs
Kim et al., Angiogenesis 2012 (Telangiectasia, Hereditary Hemorrhagic) : Conversely, BMP9 blocks EC sprouting and this is dependent on Alk1 , BMPRII/ActRII and ID1/ID3
Somekawa et al., Proc Natl Acad Sci U S A 2012 : Among them, bone morphogenetic protein (BMP) 9 and BMP10 regulate embryonic vascular development by activating their endothelial receptor ALK1 ( activin receptor-like kinase 1, also called Acvrl1 )
Briggs et al., Circ Res 2013 (Heart Septal Defects...) : Perturbation of Alk3 mediated BMP signaling from the SHF results in impaired development of the DMP and ostium primum defects