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BMP3 — SOSTDC1
Text-mined interactions from Literome
Laurikkala et al., Dev Biol 2003
:
Ectodin inhibited the activity of BMP2, BMP4,
BMP6 , and BMP7 for mouse preosteoblastic MC3T3-E1 cells, and bound to these BMPs with high affinity ... The
stimulation of
ectodin expression by
BMP was prevented by SHH and FGF4 but not by Wnt6
Kassai et al., Science 2005
:
We report that
ectodin , a secreted
bone morphogenetic protein ( BMP ) inhibitor , is expressed as a `` negative '' image of mouse enamel knots
Wu et al., J Clin Invest 2008
(Cleft Palate) :
Furthermore, we demonstrated that Pax3 directly regulates expression of
Sostdc1 , a soluble
inhibitor of
bone morphogenetic protein ( BMP ) signaling
Clausen et al., Breast Cancer Res Treat 2011
(Breast Neoplasms) :
SOSTDC1 differentially
affects Wnt3a,
BMP-2 , and BMP-7 signaling in breast cancer cells
Henley et al., Am J Physiol Endocrinol Metab 2012
(Glucose Intolerance...) :
Loss of
Sostdc1 in the setting of metabolic stress
results in altered expression of
Bmp-responsive genes in islets but did not affect expression of Wnt target genes, suggesting that Sostdc1 primarily regulates the Bmp pathway in the murine pancreas ... Furthermore, our data indicate that removal of
Sostdc1 enhances the downregulation of the closely related
Bmp inhibitors Ctgf and Gremlin in islets after 8-wk exposure to high-fat diet