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BMP4 — ICAM1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Sorescu et al., J Biol Chem 2003
(Arteriosclerosis...) :
Functionally, we show that OS and
BMP4 induced ICAM-1 expression and monocyte adhesion by a NFkappaB dependent mechanism
Jo et al., Antioxid Redox Signal 2006
(Atherosclerosis...) :
The NADPH oxidase activation by
BMP4 then
leads to ROS production, NF-kappaB activation,
intercellular adhesion molecule 1 ( ICAM-1 ) expression, and subsequent increased monocyte adhesivity of endothelial cells
Csiszar et al., Am J Physiol Heart Circ Physiol 2008
:
We found that
BMP-4 ( from 0.3 to 10 ng/ml ) in CAECs
increased O ( 2 ) ( *- ) and H ( 2 ) O ( 2 ) generation, induced NF-kappaB activation, upregulated
ICAM-1 , and induced monocyte adhesiveness to ECs