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BMP4 — PROM1
Text-mined interactions from Literome
Mizrak et al., J Pathol 2008
:
The development of such therapies will be aided by a clearer understanding of the molecular mechanisms and signalling pathways that regulate the behaviour of CD133 expressing cells, and new data outlining the
role of Wnt, Notch, and
bone morphogenetic protein ( BMP ) signalling in
CD133 ( + ) cancer stem cell regulation are discussed within
Zhang et al., Cancer Res 2012
(Carcinoma, Hepatocellular...) :
Activation of the Erk1/2 signaling pathway led to
BMP4 mediated reduction in
CD133 expression, which was reversed by treatment with MEK inhibitors