Gene interactions and pathways from curated databases and text-mining

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BMP4 — PROM1

Text-mined interactions from Literome

Mizrak et al., J Pathol 2008 : The development of such therapies will be aided by a clearer understanding of the molecular mechanisms and signalling pathways that regulate the behaviour of CD133 expressing cells, and new data outlining the role of Wnt, Notch, and bone morphogenetic protein ( BMP ) signalling in CD133 ( + ) cancer stem cell regulation are discussed within
Zhang et al., Cancer Res 2012 (Carcinoma, Hepatocellular...) : Activation of the Erk1/2 signaling pathway led to BMP4 mediated reduction in CD133 expression, which was reversed by treatment with MEK inhibitors