◀ Back to FGF9
FGF21 — FGF9
Text-mined interactions from Literome
Cohen et al., J Neurosci Res 2000
:
The
effect of
fibroblast growth factor (FGF)-9 on the expression of
FGF receptors ( FGFR ) and the major myelin proteins was examined in cultures of developing rat brain oligodendrocytes ( OLs ), using immunological techniques
Kurosu et al., J Biol Chem 2007
:
Accordingly, FGF19, but not
FGF21 ,
activates FGF signaling in hepatocytes that primarily express FGFR4 and reduces transcription of CYP7A1 that encodes the rate limiting enzyme for bile acid synthesis
Kharitonenkov et al., J Cell Physiol 2008
:
Interestingly,
FGF-21 mediated effects are heparin independent suggesting that betaKlotho plays a role in
FGF-21 activity similar to the one played by heparin in the signaling of conventional FGFs
Lü et al., Chin Med J (Engl) 2010
(Coronary Artery Disease) :
Furthermore,
FGF21 levels increased by 200 µmol/L bezafibrate could reduce CMECs apoptosis, and
inhibit FGF21 expression by shRNA induced apoptosis ( P < 0.05 )
Adams et al., PloS one 2012
:
The scaffold protein ßklotho ( KLB ) has previously been demonstrated in vitro to function as a co-factor permitting
FGF21 mediated FGF receptor activation