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AKT1 — BMP6

Text-mined interactions from Literome

Itoh et al., J Gastroenterol 2006 : Furthermore, BMP2 inhibited MSE1 cell proliferation in MTS assays and suppressed AKT phosphorylation
Segrelles et al., Mol Biol Cell 2008 (Nails, Malformed...) : Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling
Lee et al., Stem Cells 2009 : In addition, BMP-4 induced Akt phosphorylation
Johnsen et al., Cancer Res 2009 (Adrenal Cortex Neoplasms...) : This growth inhibitory effect was associated with BMP dependent reduction of AKT phosphorylation under baseline conditions and under insulin-like growth factor costimulation
Mandal et al., Endocrinology 2009 : Inhibition of PI3K/Akt signaling blocked the binding of Smads 1/5 to the CSF-1 BMP-responsive element present in the CSF-1 promoter, resulting in attenuation of Smad dependent CSF-1 transcription
Ueki et al., Glia 2013 : Interestingly, BMP/Smad1/5/8 activation downstream of PI3K/AKT signaling was also necessary for robust Müller glial proliferation, though activation of BMP/Smad1/5/8 signaling alone failed to stimulate their proliferation