Gene interactions and pathways from curated databases and text-mining

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CAV3 — ESR1

Text-mined interactions from Literome

Schlegel et al., Biochem J 2001 : Since AF-1 activity is regulated largely by phosphorylation we determined that co-expression with caveolin-1 increased the basal phosphorylation of ERalpha ( 1-282 ), but blocked the epidermal growth factor dependent increase in phosphorylation
Zschocke et al., J Biol Chem 2002 : Estrogen receptor alpha mediated silencing of caveolin gene expression in neuronal cells
Barros et al., Proc Natl Acad Sci U S A 2006 : Both ERbeta and ERalpha are necessary for optimal caveolin-1 expression
Yang et al., Acta Biochim Biophys Sin (Shanghai) 2006 : Therefore, this study was designed to see whether raloxifene regulates caveolin-1 expression and if so, whether such regulation is mediated by estrogen receptor
Boulware et al., J Neurosci 2007 : ER alpha activation of mGluR1a is dependent on CAV1, whereas CAV3 is necessary for ER alpha and ER beta activation of mGluR2/3
Sud et al., Mol Endocrinol 2010 : ERalpha is known to colocalize with caveolin 1, the major structural protein of caveolae, and caveolin 1 stimulates the translocation of ERalpha to the plasma membrane