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ESR1 — PPP5C
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
ESR1
—
PPP5C
(direct interaction, pull down)
Ikeda et al., Mol Endocrinol 2004*
-
IRef Biogrid Interaction:
ESR1
—
PPP5C
(direct interaction, two hybrid)
Ikeda et al., Mol Endocrinol 2004*
-
IRef Biogrid Interaction:
ESR1
—
PPP5C
(physical association, affinity chromatography technology)
Ikeda et al., Mol Endocrinol 2004*
-
IRef Intact Interaction:
PPP5C
—
ESR1
(physical association, anti bait coimmunoprecipitation)
Ikeda et al., Mol Endocrinol 2004*
-
IRef Intact Interaction:
PPP5C
—
ESR1
(physical association, anti tag coimmunoprecipitation)
Ikeda et al., Mol Endocrinol 2004*
-
IRef Intact Interaction:
PPP5C
—
ESR1
(physical association, two hybrid)
Ikeda et al., Mol Endocrinol 2004*
-
IRef Intact Interaction:
PPP5C
—
ESR1
(physical association, pull down)
Ikeda et al., Mol Endocrinol 2004*
Text-mined interactions from Literome
Traupe et al., Hypertension 2007
:
Within 5 minutes, selective
ERalpha activation by
PPT , but not 17beta-estradiol or the ERbeta agonist DPN, caused rapid, NO-dependent, and endothelium dependent relaxation ( 49+/-5 % ; P < 0.001 versus ethanol )
Lahm et al., Am J Physiol Regul Integr Comp Physiol 2008
(Anoxia) :
Selective
ER-alpha activation (
PPT , 5 x 10 ( -5 ) M ) rapidly ( < 20 min ) decreased phenylephrine induced vasoconstriction
Chen et al., J Bone Miner Res 2009
:
ERalpha agonist
propylpyrazoletriol (PPT) and ERbeta agonist diarylpropionitrile ( DPN )
attenuated EtOH induced
ERalpha and ERbeta gene overexpression, respectively
Thammacharoen et al., Brain Res 2009
:
The anomalously rapid eating-inhibitory effect of PPT suggests that PPT 's neuropharmacological effect differs from estradiol 's, perhaps because
PPT differentially
activates membrane versus nuclear
ER-alpha or because PPT activates non-ER-alpha membrane estrogen receptors in addition to ER-alpha