◀ Back to IL17A
IL17A — TRAF6
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Chang et al., J Biol Chem 2006
(Inflammation...) :
An earlier study found that
IL-17 activates NF-kappaB and MAPK pathways and
requires TRAF6 to induce IL-6
Rong et al., Cell Signal 2007
:
Our results indicate that ubiquitination of
IL-17R mediated by
TRAF6 plays a critical role in IL-17F signaling
Chang et al., Cell Res 2007
(Inflammation) :
IL-17A/F regulation of IL-6 and KC expression is
dependent on IL-17RA and
TRAF6
Huang et al., J Immunol 2007
:
Requirement for both JAK mediated PI3K signaling and
ACT1/TRAF6/TAK1 dependent NF-kappaB
activation by
IL-17A in enhancing cytokine expression in human airway epithelial cells
Hartupee et al., J Immunol 2009
:
IL-17 signaling for mRNA stabilization does not
require TNF receptor associated factor 6
Hot et al., Ann Rheum Dis 2011
(Arthritis, Rheumatoid) :
IL-17A and, to a lesser extent,
IL-17F induced
TRAF6 but not MyD88
Garg et al., Science signaling 2013
:
A20 associated with the E3 ubiquitin ligase
TRAF6 ( tumor necrosis factor receptor associated factor 6 ) in an
IL-17 dependent manner and restricted the IL-17 dependent activation of NF-?B and mitogen activated protein kinases