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PMEL — SKP1

Text-mined interactions from Literome

Nakajima et al., Arch Dermatol Res 2012 (Hyperpigmentation) : Real-time RT-PCR and western blotting of Ax-treated HEEs revealed that the SCF stimulated expression of tyrosinase (TYR), TYR related protein-1 (TYRP1), and Pmel17 , as well as microphthalmia associated transcription factor ( MITF ), is significantly suppressed by Ax at the transcriptional and translational levels
Wakabayashi et al., J Dermatol Sci 2013 (Lentigo) : Real-time RT-PCR and Western blotting of these NCM treated HEEs unexpectedly revealed that the EDN1+SCF stimulated steady-state levels of tyrosinase (TYR), TYR related protein-1, dopachrome tautomerase and PMEL17 as well as microphthalmia associated transcription factor ( MITF ) were significantly attenuated at the transcriptional and translational levels without any cytotoxic effects on keratinocytes and melanocytes in the HEEs