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Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
Complex of EGFR-HSPA5
(decreases)
Cai et al., J Cell Physiol 1998* Evidence: Treatment of the GRP78-underglycosylated EGFR complex with ATP resulted in a release of the underglycosylated EGFR from GRP78, indicating that the complex could be formed through the chaperone function of GRP78. In accordance with the complex formation with endoplasmic reticulum-resident GRP78, the underglycosylated EGFR could not be translocated to the cell surface. As a result, EGF could not induce expression of cyclin D3, a G1 cyclin, in the stressed cells, whereas it did in non-stressed cell...
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *