◀ Back to HSPG2

HSPG2 — RAP2B

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 400 proteins (association, cross-linking study) Humphries et al., Science signaling 2009

Text-mined interactions from Literome

Stope et al., Mol Cell Biol 2004 : PLC and Ca ( 2+ ) signaling by the EGF receptor, which activated both PLC-gamma1 and PLC-epsilon, was specifically suppressed by inactivation of Ras related GTPases with clostridial toxins and expression of dominant negative Rap2B ... EGF induced rapid and sustained GTP loading of Rap2B, binding of Rap2B to PLC-epsilon, and Rap2B dependent translocation of PLC-epsilon to the plasma membrane
vom Dorp et al., Cell Signal 2004 : In contrast, Rap2B activation and PLC stimulation induced by membrane-permeable cyclic AMP analogues, including an Epac-specific activator, or PLC stimulation caused by constitutively active Rap2B were not affected by the Gi-coupled receptors