Gene interactions and pathways from curated databases and text-mining

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MB — MYO10

Text-mined interactions from Literome

Frederiksen et al., J Agric Food Chem 2008 : Myosin thiols are suggested to be the main target for oxidative modification, as NEM treated myosin did not form radicals in the presence of hypervalent myoglobin
Hanan et al., Eur J Biochem 1995 : Thus, at cellular ionic strength in which myosin is insoluble, cross linking of myosin could still be triggered by myoglobin and H2O2 ... Based on these data, it is suggested that myoglobin induced cross linking of myosin and the consequent loss of adenosinetriphosphatase activity may be involved in muscle malfunction under hypoxia when cellular peroxidants increase and the deoxymyoglobin form prevails