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HGF — PLA2G4A
Text-mined interactions from Literome
Wu et al., Hepatology 2002
(Bile Duct Neoplasms...) :
HGF and IL-6 also
induced a rapid phosphorylation of
cPLA(2) ( within 1 minute ) but did not alter cPLA(2) and COX-2 protein expression
Adachi et al., Hepatology 1995
:
These results suggest that
HGF as well as EGF
causes AA release, probably through activation of
cPLA2 mediated by MAP kinases, and that PGs, metabolites of AA, might play a pivotal role in hepatocyte proliferation in an autocrine mechanism