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Wang et al., J Biol Chem 2008
:
5-Aza-CdR induces p53 posttranslational modifications through activation of an ATM- and Rad3 related (ATR) signaling pathway, and 5-aza-CdR induced association of replication protein A with chromatin is required for the binding of ATR to chromatin
Liu et al., J Cell Biol 2007
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Furthermore, we show that replication protein A 2 and retinoblastoma protein are both downstream targets for ATR that are important for the inhibition of DNA rereplication