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BMP2 — PKD1
Text-mined interactions from Literome
Lemonnier et al., J Biol Chem 2004
:
In contrast to the recently described PKC dependent molecular mechanism involved in activation of PKD by G protein coupled receptor agonists,
BMP-2 did not
induce a phosphorylation of
PKD on Ser744/748 ... In contrast to the recently described PKC dependent molecular mechanism involved in activation of PKD by G protein coupled receptor agonists,
BMP-2 did not
induce a phosphorylation of
PKD on Ser744/748 ... In conclusion, results presented in this study indicate that
BMP-2 can
induce activation of
PKD in osteoblastic cells by a PKC independent mechanism and that this kinase is involved in activation of JNK and p38 induced by BMP-2
Celil et al., J Biol Chem 2005
:
BMP-2 and IGF-I induced a selective phosphorylation of PKD, and
PKD was
required for mineralization