◀ Back to CASP8
CASP8 — PTX3
Text-mined interactions from Literome
Shang et al., Urology 2007
(Carcinoma, Renal Cell...) :
DAC could enhance the
PTX induced upregulation of
caspase activity and antiproliferative effect to increase the fraction of cells in the sub-G1 and G2/M phase
Shin et al., Oncol Rep 2008
(Carcinoma, Hepatocellular...) :
PTX-2 activated caspases (
caspase-3 , -8 and -9 ) and the blockade of caspase-3 activity by the caspase-3 inhibitor prevented the PTX-2 induced apoptosis in Hep3B cells
Shang et al., Cancer Lett 2009
(Prostatic Neoplasms) :
DAC enhanced the
PTX induced up-regulation of
caspase activity and antiproliferative effect, resulting in an increase of cells in subG1 and G2/M phases
Mitra et al., Molecular vision 2011
(Retinal Neoplasms...) :
PTX-NP-EpCAM had superior antiproliferation activity, increased arrested cell population at the G(2)-M phase, and
increased activation of
caspase-3 , followed by PARP cleavage in parallel with the induction of apoptosis
Yang et al., Int J Nanomedicine 2013
:
In addition, the
PTX-NPs markedly
inhibited interleukin-6 secretion, increased
caspase-8 , caspase-9, and caspase-3 expression, and induced apoptosis of tumor cells in the treated mice