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CHUK — TLR3

Pathways - manually collected, often from reviews:

• Reactome Reaction: CHUK → TLR3 (reaction) Wu et al., Nat Cell Biol 2006, Ea et al., Mol Cell 2006
• Reactome Reaction: CHUK → TLR3 (indirect_complex) Wu et al., Nat Cell Biol 2006, Ea et al., Mol Cell 2006

Text-mined interactions from Literome

Cusson-Hermance et al., J Biol Chem 2005 : These studies suggest that Rip1 uses a similar, ubiquitin dependent mechanism to activate IkappaB kinase-beta in response to TNF-alpha and TLR3 ligands
Tong et al., Cell Res 2012 : NLRC5 ablation reduces MHC class I expression, and enhances IKK and IRF3 phosphorylation in response to TLR stimulation or viral infection