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UCSC Genome Browser Gene Interaction Graph
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Gene interactions and pathways from curated databases and text-mining
◀ Back to FAS
FAS — SYK
Pathways - manually collected, often from reviews:
NCI Pathway Database FAS (CD95) signaling pathway :
FASLG/FAS (trimer)/Src/Syk complex (FAS-FASLG-SRC-SYK)
→
SYK (SYK)
(modification, collaborate)
Beier et al., J Neurosci 2005 , Letellier et al., Immunity 2010
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database FAS (CD95) signaling pathway :
FASLG/FAS (trimer)/Src/Syk complex (FAS-FASLG-SRC-SYK)
→
Src (SRC)
(modification, collaborate)
Beier et al., J Neurosci 2005 , Letellier et al., Immunity 2010
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database FAS (CD95) signaling pathway :
FASLG/FAS (trimer)/Src/Syk complex (FAS-FASLG-SRC-SYK)
→
FASLG/FAS (trimer) complex (FAS-FASLG)
(modification, collaborate)
Beier et al., J Neurosci 2005 , Letellier et al., Immunity 2010
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database FAS (CD95) signaling pathway :
SYK (SYK)
→
FASLG/FAS (trimer) complex (FAS-FASLG)
(modification, collaborate)
Beier et al., J Neurosci 2005 , Letellier et al., Immunity 2010
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database FAS (CD95) signaling pathway :
FASLG/FAS (trimer)/Src/Syk complex (FAS-FASLG-SRC-SYK)
→
PI3K Class IA family (PIK3CA/PIK3R1/PIK3CB/PIK3R1)
(modification, activates)
Beier et al., J Neurosci 2005 , Letellier et al., Immunity 2010