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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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AR — FOS

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: FOS — AR (interaction, mapped from dip)
  • STRING interaction: AR — FOS (interaction, mapped from dip)

Text-mined interactions from Literome

Ikezoe et al., Br J Cancer 2004 (Prostatic Neoplasms) : A previous study showed that c-Jun/AP-1 blocked androgen receptor (AR) signaling by inhibiting AR binding to AR response elements ( AREs ) of target genes including prostate-specific antigen (PSA)
Church et al., Prostate 2005 (Prostatic Neoplasms) : Induction of AP-1 activity by androgen activation of the androgen receptor in LNCaP human prostate carcinoma cells ... Effects of androgen activated androgen receptor on AP-1 activity were determined in the LNCaP human prostate carcinoma cell model ... Activation of androgen receptor by androgen induces changes in AP-1 activity and AP-1 factor DNA binding that may contribute significantly to androgen induced changes in prostate cancer cell growth