Perks et al., Br J Cancer 1999
(Breast Neoplasms) :
Despite inhibition of cell proliferation, IGF-I stimulation of cells in S-phase and of cyclin A levels were unaffected ; however, an IGF-I induced increase in cyclin B1 levels was inhibited by 30 %
Furlanetto et al., Mol Endocrinol 1994
(Bone Neoplasms...) :
The mRNA levels of cyclin-B1 ( a G2 cyclin ) and two cyclin dependent kinases, cdc2 and cdk2, also increased in response to IGF , but at later times