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Morino et al., Endocrinology 2001
:
Insulin induced c-Jun N-terminal kinase activation is negatively regulated by protein kinase C delta Lin et al., Carcinogenesis 2008
(Breast Neoplasms...) :
A translocation of protein kinase C (PKC)delta from the cytosol to the membrane followed by activation of extracellular signal regulated kinase ( ERK ) and c-Jun/activator protein-1 (AP-1) by TPA was demonstrated, and TPA induced MMP-9 activation and migration were inhibited by the pan PKC inhibitor, GF109203X, the specific PKCdelta inhibitor, rottlerin, an ERK inhibitor ( PD98059 ) and an AP-1 inhibitor ( curcumin )