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MPO — NFKB1
Text-mined interactions from Literome
Hassoun et al., Am J Physiol Gastrointest Liver Physiol 2002
(Intestinal Obstruction...) :
Rats subjected to I/R exhibited markedly depressed intestinal transit, histological evidence of severe injury to the ileum, increased
myeloperoxidase activity in ileal cytoplasmic extracts, and biphasic
activation of
NF-kappaB in ileal nuclear extracts
Nys et al., Clin Sci (Lond) 2002
(Bronchopneumonia...) :
NF-kappaB activation by
MPO was also demonstrated
Yang et al., Inflamm Res 2005
(Disease Progression...) :
We demonstrated that intravenous administration of endotoxin could provoke significant lung injury, which was characterized by increase of
MPO activity and wet/dry weight ratio, TNF-alpha and IL-6 expression and
NF-kappa B activation
Nys et al., Vascul Pharmacol 2005
(Lung Diseases) :
Nitric oxide related products and
myeloperoxidase in bronchoalveolar lavage fluids from patients with ALI
activate NF-kappa B in alveolar cells and monocytes ... Furthermore, in vitro studies confirmed that NO* derived species ( peroxynitrite and nitrites ) and the neutrophil enzyme
myeloperoxidase by themselves
increased the activation of
NF-kappaB , thereby arguing for an in vivo pathogenetic role of NO* related products and neutrophil enzymes to human ALI
Lin et al., J Am Soc Nephrol 2008
(Acute Kidney Injury...) :
Measures of inflammation ( number of infiltrating neutrophils,
myeloperoxidase activity, and induction of IL-6 and P-selectin ) and
activation of
NF-kappaB were lower in GC-G ( -/- ) mice compared with wild-type mice
Wijagkanalan et al., Mol Pharmacol 2008
(Pneumonia) :
DPML significantly inhibited tumor necrosis factor alpha, interleukin-1beta, and cytokine induced neutrophil chemoattractant-1 levels, suppressed neutrophil infiltration and
myeloperoxidase activity, and
inhibited NFkappaB and p38 mitogen activated protein kinase activation in the lung
Di Paola et al., Intensive Care Med 2009
(Hypertension...) :
Administration of glycyrrhizin, significantly reduced the ( a ) fall of mean arterial blood pressure, ( b ) mortality rate, ( c )
myeloperoxidase (MPO) activity, ( d ) production of pro-inflammatory cytokines [tumor necrosis factor-alpha ( TNF-alpha ) and interleukin-1beta (IL-1beta) ], ( e ) histological evidence of gut injury, ( f ) immunoreactivity of nitrotyrosine, ( g ) poly ADP-ribose ( PAR ) formation, ( h ) the expression of ICAM-1 and P-selectin, ( i )
activation of
nuclear factor-kappaB (NF-kappaB) and ( j ) signal transducer and activator transcription-3 ( STAT-3 ) induced by splanchnic artery occlusion-reperfusion shock
Chen et al., J Biomed Sci 2010
(Burns) :
Commensal depletion decreased TLR4 expression as well as
NF-kappaB activation of intestine,
myeloperoxidase (MPO) activity as well as TNFalpha expression of lung, and bacterial killing activity of peritoneal cells