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HIF1A — NOS2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Hu et al., Chin Med J (Engl) 2002
(Anoxia...) :
Hypoxia-inducible factor 1 alpha upregulates the expression of inducible
nitric oxide synthase gene in pulmonary arteries of hyposic rat
Wang et al., Bone 2004
:
Human osteoblasts were treated with or without US stimulation ( 200 micros pulse, 1 kHz at 30 mW/cm2 ) for 20 min. Cells were subjected to assessment of VEGF-A expression, NO production,
nitric oxide synthase (NOS) catalytic activities, and
HIF-1alpha transactivation
Li et al., Circ Res 2008
(Disease Models, Animal...) :
Two weeks after ODN transfection, the
HIF-1alpha binding activities were significantly inhibited by 45 %, and high salt induced increases of
nitric oxide synthase-2 and heme oxygenase-1 transcriptions were also
inhibited by 70 % and 61 % in the renal medulla from decoy rats