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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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NGF — NOS2

Text-mined interactions from Literome

Macdonald et al., Neuroreport 2000 (Adrenal Gland Neoplasms...) : Tumor necrosis factor-alpha and nerve growth factor synergistically induce iNOS in pheochromocytoma cells ... We found that while TNFalpha and NGF alone were unable to induce iNOS , their simultaneous addition resulted in iNOS induction and the release of nitric oxide ... Our results suggest that synergistic iNOS induction by TNFalpha and NGF may occur in selective population of NGF-responsive neurons in the presence of elevated CNS levels of TNFalpha
Calza et al., Proc Natl Acad Sci U S A 2001 : NGF , either alone or associated with 6-OHDA, also induced a significant up-regulation of NADPH diaphorase, neuronal nitric oxide synthase , and vascular endothelial growth factor expression in scg neurons
Kalisch et al., J Neurochem 2003 : Modulation of nerve growth factor induced activation of MAP kinase in PC12 cells by inhibitors of nitric oxide synthase
Thomas et al., Journal of neuroinflammation 2005 : We previously showed in NGF-responsive PC12 cells that tumor necrosis factor alpha (TNFalpha) and NGF synergistically induce the expression of the free-radical producing enzyme inducible nitric oxide synthase (iNOS)
Pan et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2011 (Inflammation) : NGF induced the mRNA expression of iNOS and substance P in dorsal root ganglion sensory neuron cells, and IFN-? increased NGF induced iNOS mRNA expression
Chang et al., Neurochem Int 1997 : The nerve growth factor (NGF) induced neurite outgrowth and nitric oxide synthase expression appeared normal in PC12 cells treated with a sublethal dose of 25-OH-cholesterol