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CCL28 — TP53
Text-mined interactions from Literome
Lin et al., Food Chem Toxicol 2007
(Colonic Neoplasms) :
As for apoptosis,
MEC may
induce upregulation of
p53 and downregulation of Bcl-2, thus causing the release of cytochrome C from mitochondria and the translocation of apoptosis inducing factor ( AIF ) to the nucleus
Komura et al., Exp Cell Res 2007
(Neoplasms) :
2,5-MeC also
activated endogenous
p53 and induced apoptosis in U2OS cells
Takahashi et al., Int J Cancer 1993
(Breast Neoplasms) :
Whereas the increases in DNA synthesis and p53 phosphorylation were inhibited by antibody to the IGF-I receptor and by 2,5-Mec, the nuclear exclusion of
p53 was
prevented by the antibody and also, although not significantly, by
2,5-Mec