UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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CTNND1 — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Intact Interaction: Complex of 88 proteins (association, tandem affinity purification) Agrawal et al., Cell cycle (Georgetown, Tex.) 2010
IRef Intact Interaction: Complex of 58 proteins (physical association, anti tag coimmunoprecipitation) Sowa et al., Cell 2009

Text-mined interactions from Literome

Behrens et al., Anticancer Res 2001 (Breast Neoplasms) : Different localization of CAS might affect its role not only for chromosome segregation, proliferation and apoptosis, but also its function in nuclear transport of proteins like retinoblastoma-gene-product, p53 and BRCAl
Liao et al., BMB Rep 2008 (Neoplasms) : CAS overexpression enhanced p53 accumulation induced by doxorubicin, 5-fluorouracil, cisplatin, tamoxifen, and etoposide