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CTSG — F2R

Pathways - manually collected, often from reviews:

• KEGG Neuroactive ligand-receptor interaction: CTSG/F2/GZMA/PLG/PRSS1/PRSS2/PRSS3 → F2R/F2RL1/F2RL2/F2RL3/PARD3 (protein-protein, activation)
  

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: CTSG — F2R (in vitro) Loew et al., Biochemistry 2000

Text-mined interactions from Literome

Ryu et al., J Biol Chem 2000 : However, thrombin receptor agonist peptide ( an agonist of protease activated receptor-1 (PAR-1) ), could not mimic the effect of thrombin, and cathepsin G , a PAR-1 inhibitor , did not reduce the effect of thrombin
Meli et al., J Neurochem 2001 (Glioma) : The effect of THR, but not that of PAR1-AP, was significantly inhibited by hirulog ( TM ) ( 60 microg/mL ), a specific and stochiometric THR inhibitor or by cathepsin-G ( 40 mU/mL ), an inhibitor of PAR-1
Tang et al., J Mol Neurosci 2007 : Cathepsin-G , a thrombin PAR-1 inhibitor , reversed significantly ( p < 0.05 ) the effect of thrombin on AQP4 mRNA and protein expression in astrocytes