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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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IFNG — MMP16

Text-mined interactions from Literome

Nold et al., Naunyn Schmiedebergs Arch Pharmacol 2003 : Whereas IL-18 and TNFalpha induced the protease, MMP-9 release was not mediated by IFNgamma
Wang et al., World J Gastroenterol 2008 (Liver Cirrhosis) : Both Cpd 861 and IFN-gamma reduced the mRNA levels of collagen type III, MMP-2 and TGF-beta1
Nareika et al., Atherosclerosis 2009 (Atherosclerosis...) : Results showed that high glucose and IFN gamma had a synergistic effect on the expression of MMP-1, MMP-9 and IL-1 beta
Mann et al., Ann Otol Rhinol Laryngol 1995 (Carcinoma, Squamous Cell...) : Supernatants of HNSCC cell lines SCC-25 and FADU stimulated with interleukin (IL)-1 alpha and IL-1 beta demonstrated modest induction of 92 kd GL production by zymogram analysis when compared with controls ; IL-2, IL-6, and interferon-gamma had no consistent effect on MMP production
Varga et al., Adv Exp Med Biol 1996 : Supplementation with tryptophan completely overcame the inhibitory effects of interferon-gamma on MMP mRNA expression and metalloproteinase secretion into the media ... These results indicate that oxidative tryptophan metabolism mediates the effects of interferon-gamma on MMP gene expression in human fibroblasts