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BCR — CHUK

Text-mined interactions from Literome

Petro et al., J Biol Chem 2001 : Specifically, pharmacologic agents that block the action of either PLC-gamma2 or its second messengers prevent BCR induced activation of IkappaB kinase
Patke et al., Curr Opin Immunol 2004 : BCR signaling leads to activation of the inhibitor of NF-kappa B kinase (IKK) complex via Carma1, Bcl10 and MALT1, whereas BAFF-R engagement promotes processing of NF-kappa B2 protein p100, which is dependent on NF-kappa B-inducing kinase (NIK) and IKK alpha
Shinohara et al., J Exp Med 2007 : 23 : 561-574 ) to play a crucial role in B cell receptor (BCR) mediated IkappaB kinase (IKK) activation through phosphorylation of caspase recruitment domain 11, Bimp3 ( CARMA1 ) ... We show that PKCbeta mediates phosphorylation of CARMA1 on Ser668, which in turn is essential for BCR mediated CARMA1-Bcl10-mucosal associated lymphoid tissue 1 ( MALT1 ) association and subsequent IKK activation
Kometani et al., J Exp Med 2011 : These mice had impaired T cell independent type II antibody responses in vivo and diminished IKK-ß activation and cellular responses to B cell receptor (BCR) cross linking in vitro