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BCAR1 — RAC2

Text-mined interactions from Literome

Hsia et al., J Cell Biol 2003 (Neoplasm Invasiveness...) : Cell invasion was linked to transient FAK accumulation at lamellipodia, formation of a FAK-Src-p130Cas-Dock180 signaling complex, elevated Rac and c-Jun NH2-terminal kinase activation , and increased matrix metalloproteinase expression and activity
Smith et al., J Cell Biol 2008 (Neoplasm Invasiveness) : We show that uPAR cooperates with integrin complexes containing beta ( 3 ) integrin to drive formation of the p130Cas-CrkII signaling complex and activation of Rac , resulting in a Rac-driven elongated-mesenchymal morphology, cell motility, and invasion