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BDNF — VIP
Text-mined interactions from Literome
Villuendas et al., Brain Res Mol Brain Res 2001
:
BDNF increased
VIP and SS gene expression and peptide production
Cellerino et al., J Comp Neurol 2003
:
The animals were sacrificed on P22, P40, P60, P80, and P120, and VIP expression in their retinas was detected by immunohistochemistry ( P22, P40 ) and by radioimmunoassay ( RIA ; P22, P40, P60, P80, P120 ) to assess the time course of
BDNF effects on
VIP
Pellegri et al., Eur J Neurosci 1998
:
In view of the neurotrophic effect of vasoactive intestinal peptide (VIP), the
regulation of
brain derived neurotrophic factor (BDNF) expression by
VIP and the related peptide pituitary adenylate cyclase activating polypeptide ( PACAP ) was analysed by Northern blot in primary cultures of cortical neurones ... In primary cultures of cortical neurones, induction of BDNF mRNA by VIP and PACAP is completely inhibited by the N-methyl-D-aspartate ( NMDA ) receptor antagonists MK-801 and AP5, therefore indicating that
VIP and PACAP do not
stimulate BDNF expression directly but rather by potentiating the effect of glutamate tonically released by neurones and acting at NMDA receptors