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MAPK1 — VIP
Text-mined interactions from Literome
Bartoe et al., J Neurochem 2000
:
Furthermore, LIF stimulated
MAPK activation negatively
regulates this
VIP reporter gene induction
Moody et al., Regul Pept 2002
(Lung Neoplasms) :
PACAP-27 or PACAP-38 ( 100 nM ) but not PACAP28-38 or
VIP caused increased
MAPK tyrosine phosphorylation using NCI-H1299 cells
Fernández et al., J Mol Endocrinol 2005
:
Studies in GH4C1 cells, with an expression vector for Rap1 GTPase activating protein ( Rap1 GAP1 ), demonstrated reduced
VIP induced
MAPK activation, indicating that VIP dependent activation of the extracellular signal regulated kinase ( ERK ) pathway requires PKA-Rap1 signaling ... IGF-I and
VIP stimulation of CRE mediated transcription
required activation of both
Ras-MAPK and cAMP/PKA signaling ... In summary, we showed that IGF-I and
VIP stimulated
MAPK activity and the phosphorylation of CREB in pituitary cells
Djamei et al., Science 2007
(MAP Kinase Signaling System) :
MAPK dependent phosphorylation of
VIP1 is necessary for VIP1 mediated Agrobacterium T-DNA transfer, indicating that Agrobacterium abuses the MAPK targeted VIP1 defense signaling pathway for nuclear delivery of the T-DNA complex as a Trojan horse
Yu et al., Neuropeptides 2010
:
In addition,
VIP treatment
induced rapid phosphorylation of ERK1/2 and
p38MAPK , and PD98059 and SB203580 were able to inhibit VIP induced phosphorylation of ERK1/2 and p38MAPK, respectively