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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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CASP4 — SETBP1

Text-mined interactions from Literome

Shinohara et al., Int J Mol Med 2004 : SEB induced the activation of caspase-3 and -8, and pre-treatment with z-VAD-fmk, a broad-spectrum inhibitor of caspases, prevented the induction of apoptosis
Lin et al., Allergy 2007 (Dermatitis, Atopic) : SEB-reactive ( TCRVbeta3+, Vbeta12+, and Vbeta17+ ) CD4+ T cells from AD patients were more resistant to SEB induced caspase-3 activation and SEB induced decrease of Bcl-2 and Bcl-2 mRNA than those from healthy subjects ... Exogenously added IL-4 inhibited SEB induced caspase-3 activation and SEB induced decrease of Bcl-2 and Bcl-2 mRNA in SEB-reactive CD4+ T cells from healthy subjects ... Inhibition of endogenous IL-4 by using anti-IL-4 neutralizing antibodies up-regulated SEB induced caspase-3 activation and SEB induced decrease of Bcl-2 and Bcl-2 mRNA in SEB-reactive CD4+ T cells from AD patients
Laiosa et al., Toxicol Appl Pharmacol 2007 : Moreover, activation of caspase 8 and caspase 3 was reduced by more than 60 % in CD95 deficient MRL/MpJ-Fas ( lpr ) mice demonstrating that caspase 8 and 3 activation in response to SEB is CD95 dependent