UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

TCF7 — TYRP1

Text-mined interactions from Literome

Fang et al., Biochem Biophys Res Commun 1999 (Melanoma) : Role of microphthalmia transcription factor in regulation of melanocyte differentiation marker TRP-1
Aoki et al., Life Sci 2002 : The microphthalmia associated transcription factor ( MITF ), which belongs to the family of bHLH-LZ type transcription factors, regulates the transcription of melanogenesis related enzyme genes such as the tyrosinase and TRP-1 genes
Yen et al., Evidence-based complementary and alternative medicine : eCAM 2012 : Further, PNM exhibited a significant antimelanogenesis effect ( P < 0.05 ) by reducing the levels of phospho-cAMP response element binding protein and microphthalmia associated transcription factor ( MITF ), inhibiting the synthesis of tyrosinase, tyrosinase related protein-1 (TRP-1) , and TRP-2, and decreasing the cellular melanin content