◀ Back to GCG

GCG — MBP

Text-mined interactions from Literome

Kolehmainen et al., Neurochem Int 1995 : Mechanism of the myelin basic protein induced insulin and glucagon release from isolated rat pancreatic islets ... Glucose at concentrations of 10 or 15 mM did not suppress MBP stimulated glucagon release ... Caffeine evoked increase in intracellular Ca2+ was without effect on MBP stimulated insulin or glucagon release but enhanced glucose induced insulin release ... Ruthenium red inhibited both MBP- and glucose stimulated insulin release as well as MBP induced glucagon release ... The relation of MBP induced insulin and glucagon release to Ca2+ concentration is probably explained by enhanced self-aggregation of MBP or by increased ability of MBP to interact with islet cell membranes in the absence of Ca2+, or both
Kolehmainen et al., Pancreas 1998 : Interaction of MBP with the secretion granules is suggested to play a role in MBP induced insulin and glucagon release, and some hormone might be released by leakage