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CALM1 — TFP1

Text-mined interactions from Literome

Olivero et al., Biochem Pharmacol 2001 : These two results suggest little direct dependence between the PCB induced activation of iPLA2 and increase in [ Ca2+ ] i. Calmidazolium and W7 [ N- ( 6-aminohexyl ) -5-chloro-1-naphthalenesulfonamide ], two chemically distinct calmodulin inhibitors, inhibited Aroclor 1242 induced PLA2 activity, whereas trifluoperazine (TFP) , another inhibitor of calmodulin , had no effect at noncytotoxic concentrations
Huotari et al., J Cell Physiol 1992 : Elevation of intracellular calcium level by A23187 or treatment with trifluoperazine (TFP) , a calmodulin inhibitor , did not have any drastic effect on the fodrin distribution as judged by immunofluorescence microscopy
Liu et al., J Biomed Sci 2004 : Trifluoperazine (TFP) , a calmodulin inhibitor , was capable of counteracting the inhibition of DHEA on high K ( + ) -induced secretions
Nakabayashi et al., Biol Cell 1992 : Trifluoperazine (TFP) , a calmodulin inhibitor , suppressed lymphocyte stimulation as assessed by 3H-thymidine incorporation into DNA of lectin stimulated lymphocytes
Kaneko et al., Eur J Neurosci 2006 (Mechanotransduction, Cellular) : Extracellular application of BAPTA-AM ( 25 microM ), an intracellular Ca2+ chelator, and TFP ( 20 microM ), a specific inhibitor of calmodulin , reduced endocytic activity, as did depolarization of the whole cell
Trischitta et al., Comp Biochem Physiol A Mol Integr Physiol 2008 (Ion Channel Gating) : The observation that the effect of gossypol on both I ( sc ) and g ( t ) was modified by the pretreatment with TFP , a calmodulin inhibitor , suggests that the substance acts via a Ca2+ calmodulin pathway and excludes the possibility that the observed effects were due to a cytotoxic action
Richter et al., J Leukoc Biol 1990 : Trifluoroperazine (TFP) , a dual protein kinase C and calmodulin inhibitor , significantly inhibited the LT-mediated secretion of lactoferrin from adherent granulocytes
Anaise et al., Transplantation 1990 : Previous studies have shown a protective effect of trifluoperazine (TFP) , a calmodulin inhibitor , upon the microcirculation of cold stored kidneys
Grief et al., Eur J Cancer Clin Oncol 1989 (Carcinoma, Squamous Cell...) : When exposed to trifluoperazine (TFP) , an inhibitor of calmodulin , cell growth was reduced primarily in the cultures of normal keratinocytes
Kurebayashi et al., J Physiol 1988 : 1. Since it has been demonstrated that trifluoperazine (TFP) increases the affinity for Ca2+ of troponin C as well as calmodulin , the effect of TFP was examined on the Ca2+ induced tension in mechanically skinned fibres isolated from frog skeletal muscle and on Ca2+ dependent ATPase activity of myofibrils from similar frog skeletal muscle
Bjerregaard et al., Acta Physiol Scand 1988 : Calmidazolium and chlorpromazine stimulated the SCC to the same degree and in the same concentration range as TFP, suggesting that the effect of TFP was not mediated by the Ca2+-calmodulin complex
Antonelli et al., Int J Immunopharmacol 1987 (Dermatitis, Contact) : Topical application of trifluoroperazine (TFP) , a calmodulin inhibitor , on the skin of CBA mice previously immunized with 2-phenyl-4-ethoximethylene-oxazolone ( oxazolone ) blocks the expression phase of contact sensitivity
Chin et al., J Urol 1986 : The addition of trifluoperazine, ( TFP , a calmodulin inhibitor ) to the Euro-collins ' resulted in only a 9 % drop in T1 after 72 hours
Ganguly et al., Biochem Int 1987 (Diarrhea...) : In the presence of calmodulin inhibitor, trifluoperazine (TFP) , the transport of Na+ and Cl- increased significantly ( p less than 0.05 ) as compared to in the absence of inhibitor while transport of Ca2+ remained unaltered
Kwok et al., Int J Radiat Oncol Biol Phys 1986 (Neoplasms, Experimental) : Treatment of small EMT6 spheroids ( approximately 250 microns in diameter ) with trifluoperazine (TFP) , a calmodulin inhibitor , before drug exposure did not alter cellular response to adriamycin (ADM) ( 5 micrograms/ml ), CCNU ( 5 micrograms/ml ) or vincristine ( VCR ) ( 1 micrograms/ml )
Raphael et al., Am J Physiol 1984 : These results indicate that the histamine-sensitive adenylate cyclase may be the site of TFP inhibition and Ca2+-calmodulin regulation ; since these drugs inhibited stimulation by DBcAMP plus IBMX, they may also be exerting additional effects distal to cAMP generation
Smith et al., Immunology 1981 : Trifluoperazine (TFP) , an inhibitor of calmodulin ( a calcium binding protein ), caused a dose related inhibition of FMLP elicited degranulation and O2- production in the presence of absence of extracellular calcium
Bellin et al., Mol Cell Endocrinol 1983 : The FSH effect was blocked by TFP , an inhibitor of calmodulin , but cAMP or theophylline overcame the effect of TEP
Wong et al., Calcif Tissue Int 1983 : In addition, PTH induced decrease in citrate decarboxylation was inhibited by low doses of TFP , an inhibitor of calmodulin and calcium dependent, phospholipid-sensitive protein kinases, in contrast to 1,25 ( OH ) 2D3, whose effects were not reduced by this agent
Anaise et al., Transplantation 1984 : Addition of trifluoperazine (TFP) , a powerful calmodulin inhibitor to Collins ' flush solution has exerted a significant protective effect on the cold preserved kidney, with successful autotransplantation of 80 % of preserved kidneys ( 4 of 5 ) after 72 hr of storage
Carnegie et al., Biol Reprod 1984 : While FSH stimulated progesterone production by both cell groups was lowered by the calmodulin inhibitor, 1- [ bis ( p-chlorophenyl ) methyl ] -3- [ 2,4-dichloro-beta- ( 2,4-dichlorobenzy loxy ) phenethyl ] imidazolium chloride ( R24571 ), cyclic AMP production by PMSG-cells in response to both FSH and LH was significantly reduced by R24571 and trifluoperazine (TFP) , another calmodulin inhibitor
Bilozur et al., Exp Cell Res 1982 : When the recompaction medium contained trifluoperazine (TFP) ( 0.05 mM ), an inhibitor of the calcium dependent protein calmodulin , the embryos failed to recompact
Alexander et al., J Surg Res 1995 : TFP , a calmodulin inhibitor , had an effect similar to A23187, although reducing SMC uptake of LDL ( P = 0.015 )
Huang et al., Eur J Biochem 1998 : The conformations of isolated rabbit fast myosin light chains ( LCs ) were modified using trifluoperazine (TFP) , the hydrophobic calmodulin inhibitor