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CAPN5 — TNF
Text-mined interactions from Literome
Wang et al., J Hepatol 2001
(Reperfusion Injury) :
Cytoprotective effect of prednisolone in hepatic IR injury was closely associated with suppression of
IL-beta/TNF-alpha production and
calpain mu
activation
Zhao et al., J Neurosci Res 2001
:
Results of this study suggest
TNF-alpha may
induce caspase-3 activation but not
calpain activation in septo-hippocampal cultures and that this activation of caspase-3 at least partially contributes to TNF-alpha induced apoptosis
Coward et al., Clin Exp Allergy 2004
:
The NF-kappaB inhibitors,
calpain inhibitor 1 ( 10 microm ), pentoxifylline ( 0.5 mm ), pyrrolidine dithiocarbamate ( PDTC, 10 microm ) or gliotoxin ( 1 pg/mL )
reduced the generation of GM-CSF,
TNF-alpha and IL-8 in parallel with their inhibition of NF-kappaB
Morita et al., Biochem Biophys Res Commun 2006
(Arthritis, Rheumatoid) :
Tumor necrosis factor ( TNF-alpha ) stimulation
induced increased expression of mu-calpain,
m-calpain , and MMP-3 in these cells, as well as the release of calpain and MMP-3 into the culture medium
Li et al., Cardiovasc Res 2009
(Disease Models, Animal...) :
gp91(phox)-NADPH oxidase mediated
calpain-1 activation
induces caspase-3 activation and
TNF-alpha expression in cardiomyocytes during LPS stimulation