UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to CDK5

CDK5 — DPYSL2

Pathways - manually collected, often from reviews:

KEGG Axon guidance: CDK5 → DPYSL2 (protein-protein, activation)
Reactome Reaction: DPYSL2 → CDK5 (indirect_complex)
Reactome Reaction: DPYSL2 → CDK5 (reaction) Sasaki et al., Neuron 2002, Deo et al., EMBO J 2004, Schmidt et al., Adv Exp Med Biol 2007

Text-mined interactions from Literome

Lin et al., Biochem Biophys Res Commun 2008 : CDK5 , a kinase that regulates CRMP-2 in axonal outgrowth, was required for the interaction between neurofibromin and CRMP-2
Crews et al., Molecular neurodegeneration 2011 : CDK5 mediated CRMP2 phosphorylation was significantly increased in the hippocampus of patients with HIV encephalitis and in gp120 transgenic mice, and this effect was rescued by genetic down-modulation of CDK5 in the mouse model
Brittain et al., FEBS Lett 2012 : Cdk5 mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2